ЭКОЛОГО-ЭПИДЕМИОЛОГИЧЕСКИЙ АНАЛИЗ ВЛИЯНИЕ ТЯЖЕЛЫХ МЕТАЛЛОВ НА РАЗВИТИЕ ОСТЕОПОРОЗА СРЕДИ НАСЕЛЕНИЯ УЗБЕКИСТАНА (ДИАГНОСТИКА И ПРОГНОЗ)

Abstract

The article provides a comprehensive analysis of the influence of heavy metals (Pb, Cd, Cr, Zn) on the development of osteoporosis in the population of Uzbekistan, taking into account unique endemic factors (vitamin D deficiency, soil geochemistry), unfavorable environmental conditions (air, water, soil pollution from industry, transport, construction) and other epidemiological features.

The pathogenesis of toxic effects on bone tissue is described in detail, data on the concentrations of pollutants and their excess of the WHO MAC are presented. Clinical manifestations, modern diagnostic methods (including REMS technology) and treatment strategies are reviewed. Based on an analysis of current dynamics and government programs, a forecast of morbidity until 2030 is given with the proposal of preventive measures.